PKC iota 抗体
(Protein Kinase C, iota (PRKCI))
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008].
recommended
recommended
PRKCI 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G11 unconjugated
recommended
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Find PKC iota 抗体 for a variety of species such as anti-Human PKC iota, anti-Mouse PKC iota, anti-Rat PKC iota. The species listed below are among those available. Click on a link to go to the corresponding products.
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Reactivity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
100 μL
Datasheet
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Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Validations
Cat. No.
ABIN6944558
Quantity
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Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6944559
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6976464
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6977325
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN6978186
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our PKC iota 抗体
: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).: "Significance and expression of atypical protein kinase C-iota in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 154, Issue 1, pp. 143-9, (2009) (PubMed).
: "Correlation of aPKC-iota and E-cadherin expression with invasion and prognosis of cholangiocarcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 1, pp. 70-5, (2008) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS." in: Journal of biomolecular NMR, Vol. 26, Issue 4, pp. 373-4, (2003) (PubMed).
: "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52524-30, (2003) (PubMed).
: "Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 42830-40, (2002) (PubMed).
: "NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival." in: Oncogene, Vol. 20, Issue 35, pp. 4777-92, (2001) (PubMed).
: "CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells." in: Oncogene, Vol. 20, Issue 31, pp. 4258-69, (2001) (PubMed).
: "Specific cellular proteins associate with angiotensin-converting enzyme and regulate its intracellular transport and cleavage-secretion." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23253-8, (2000) (PubMed).
Aliases for PKC iota 抗体
protein kinase C iota (PRKCI) 抗体protein kinase C, iota (prkci) 抗体
protein kinase C, iota (Prkci) 抗体
protein kinase C iota (Prkci) 抗体
2310021H13Rik 抗体
AI427505 抗体
aPKClambda 抗体
aPKC[l] 抗体
DXS1179E 抗体
hal 抗体
has 抗体
mKIAA4165 抗体
nPKC-iota 抗体
PKC 抗体
PKCI 抗体
Pkci 抗体
Pkcl 抗体
PKClambda 抗体
PRKCI 抗体
Prkcl 抗体
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