PKC zeta 抗体
(Protein Kinase C, zeta (PRKCZ))
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our PKC zeta 抗体
: "PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment." in: Tumour biology, Vol. 39, Issue 6, pp. 1010428317701442, (2017) (PubMed).
: "Metabolic maintenance of cell asymmetry following division in activated T lymphocytes." in: Nature, Vol. 532, Issue 7599, pp. 389-93, (2016) (PubMed).
: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).
: "Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions." in: Journal of biochemistry, Vol. 133, Issue 1, pp. 1-7, (2003) (PubMed).
: "Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes." in: European journal of biochemistry / FEBS, Vol. 216, Issue 2, pp. 597-606, (1993) (PubMed).
: "The cDNA sequence encoding human protein kinase C-zeta." in: Gene, Vol. 132, Issue 2, pp. 305-6, (1993) (PubMed).
: "Metabolic maintenance of cell asymmetry following division in activated T lymphocytes." in: Nature, Vol. 532, Issue 7599, pp. 389-93, (2016) (PubMed).
: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).
: "Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions." in: Journal of biochemistry, Vol. 133, Issue 1, pp. 1-7, (2003) (PubMed).
: "Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes." in: European journal of biochemistry / FEBS, Vol. 216, Issue 2, pp. 597-606, (1993) (PubMed).
: "The cDNA sequence encoding human protein kinase C-zeta." in: Gene, Vol. 132, Issue 2, pp. 305-6, (1993) (PubMed).
Aliases for PKC zeta 抗体
protein kinase C zeta L homeolog (prkcz.L) 抗体protein kinase C zeta (PRKCZ) 抗体
protein kinase C zeta (prkcz) 抗体
protein kinase C, zeta (PRKCZ) 抗体
protein kinase C, zeta (Prkcz) 抗体
protein kinase C zeta (Prkcz) 抗体
protein kinase C, zeta (prkcz) 抗体
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PKC-ZETA 抗体
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pkcz 抗体
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prkcz-A 抗体
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R74924 抗体
si:ch211-150o23.4 抗体
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