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PKC zeta 抗体 (N-Term)

PRKCZ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01027 unconjugated
产品编号 ABIN391018
发货至: 中国
  • 抗原 See all PKC zeta (PRKCZ) 抗体
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    抗原表位
    • 38
    • 29
    • 15
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    AA 166-197, N-Term
    适用
    • 121
    • 64
    • 43
    • 9
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    • 5
    • 3
    • 3
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    • 2
    • 1
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    宿主
    • 133
    • 3
    • 1
    克隆类型
    • 122
    • 15
    多克隆
    标记
    • 62
    • 10
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    • 5
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    This PKC zeta antibody is un-conjugated
    应用范围
    • 104
    • 63
    • 39
    • 26
    • 26
    • 20
    • 19
    • 10
    • 7
    • 7
    • 2
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PKC zeta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta.
    克隆位点
    RB01027
    亚型
    Ig Fraction
    Top Product
    Discover our top product PRKCZ Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lerner-Marmarosh, Miralem, Gibbs, Maines: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).

  • 抗原
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    别名
    PKC zeta (PRKCZ 产品)
    别名
    TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
    背景
    Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
    分子量
    67660
    基因ID
    5590
    NCBI登录号
    NP_001028753, NP_001028754, NP_001229803, NP_002735
    UniProt
    Q05513
    途径
    NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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