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PKC iota 抗体 (AA 100-300)

The 小鼠 单克隆 anti-PKC iota antibody is suitable to detect PKC iota in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7869855
发货至: 中国
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Quick Overview for PKC iota 抗体 (AA 100-300) (ABIN7869855)

抗原

See all PKC iota (PRKCI) 抗体
PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PKC iota antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PRKCI-4911
  • 抗原表位

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    AA 100-300

    原理

    PRKCI Antibody / PKC iota

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 100-300 was used as the immunogen for the PRKCI antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the PRKCI antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PRKCI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

    别名

    PRKCI

    背景

    Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC i 1/2L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

    UniProt

    P41743

    途径

    Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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