anti-大鼠 Insulin 抗体 for Enzyme Immunoassay

Recommended Insulin Antibody (supplied by: Log in to see )

抗原
Insulin (INS) 抗体
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
适用
牛, 人, 小鼠, 猪, 大鼠
951
468
368
349
238
194
45
11
9
8
7
7
6
3
3
2
2
2
2
2
1
1
1
1
1
1
1
宿主
小鼠
785
196
49
9
4
2
1
克隆类型
单克隆
标记
This Insulin antibody is un-conjugated
52
41
36
21
20
20
20
15
15
15
13
13
13
13
13
13
13
10
9
9
7
7
7
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
应用范围
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
461
356
275
269
258
237
180
118
106
67
66
31
24
23
21
8
7
5
4
4
4
3
2
2
2
1
1
1
1
1
1
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产品编号 ABIN112214
$ 434.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN112204 EIA IHC (fro) Mouse IgG1 Log in to see 5E4-3 0
1 ABIN113504 EIA IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1

General

抗原 Insulin (INS) 抗体
适用 牛, 人, 小鼠, 猪, 大鼠
(951), (468), (368), (349), (238), (194), (45), (11), (9), (8), (7), (7), (6), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
宿主 小鼠
(785), (196), (49), (9), (4), (2), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This Insulin antibody is un-conjugated
(52), (41), (36), (21), (20), (20), (20), (15), (15), (15), (13), (13), (13), (13), (13), (13), (13), (10), (9), (9), (7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
应用范围 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(461), (356), (275), (269), (258), (237), (180), (118), (106), (67), (66), (31), (24), (23), (21), (8), (7), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 找到1个引用
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Insulin抗体详情

Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN112214) 图像
特异性 This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.Aff. Const.:6.3 x 108 M-1
交叉反应 (详细) Also reacts to: Proinsulin
纯化方法 Affinity Chromatography on Protein A
免疫原 Recombinant Human Insulin.
克隆位点 D3E7 (5B6-6)
亚型 IgG1
Plasmids, Primers & others

Insulin目标详情

Insulin抗体详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN112214) 图像 回页首
抗原
别名 Insulin (INS Antibody 摘要)
背景 Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
基因ID 3630
NCBI登录号 NP_000198
UniProt P01308
途径 NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

使用细节

Insulin抗体详情 Insulin目标详情 贮存及处理 References for anti-Insulin antibody (ABIN112214) 图像 回页首
应用备注 Immunohistochemistry on Frozen Sections. ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Captureantibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Insulin抗体详情 Insulin目标详情 使用细节 References for anti-Insulin antibody (ABIN112214) 图像 回页首
浓度 1.0 mg/mL
缓冲液 PBS, 0.09 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN112214)

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 图像 回页首
背景

Qin, Jiao, Chen, Zhou, Liang, Zhong: "Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival." in: Life sciences, Vol. 84, Issue 23-24, pp. 810-6, 2009

图像

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN112214) 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Insulin (INS) antibody (ABIN112214) Staining of paraffin embedded human pancreas with mouse anti rat Insulin.