anti-大鼠 Insulin 抗体 for Enzyme Immunoassay

Recommended Insulin Antibody (supplied by: Log in to see )

抗原
Insulin (INS) 抗体
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
适用
人, 小鼠, 大鼠
1004
509
388
387
245
197
47
11
9
8
7
7
6
3
3
2
2
2
2
1
1
1
1
1
1
1
1
宿主

833
195
50
16
4
2
1
克隆类型
多克隆
标记
This Insulin antibody is un-conjugated
53
43
38
28
27
22
22
19
17
17
15
14
14
14
14
14
14
14
9
9
9
8
8
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
应用范围
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
501
390
291
285
259
237
189
119
106
67
66
31
25
23
21
8
7
6
5
4
4
3
2
1
1
1
1
1
1
1
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产品编号 ABIN372838
$ 456.50
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN112214 EIA IHC (fro) IHC (p) Mouse IgG1 Log in to see D3E7 (5B6-6) 1
1 ABIN112204 EIA IHC (fro) Mouse IgG1 Log in to see 5E4-3 0
1 ABIN113504 EIA IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1

General

抗原 Insulin (INS) 抗体
适用 人, 小鼠, 大鼠
(1004), (509), (388), (387), (245), (197), (47), (11), (9), (8), (7), (7), (6), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
宿主
(833), (195), (50), (16), (4), (2), (1)
克隆类型
多克隆
标记 This Insulin antibody is un-conjugated
(53), (43), (38), (28), (27), (22), (22), (19), (17), (17), (15), (14), (14), (14), (14), (14), (14), (14), (9), (9), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
应用范围 Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(501), (390), (291), (285), (259), (237), (189), (119), (106), (67), (66), (31), (25), (23), (21), (8), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3个引用可参考
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Insulin抗体详情

Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN372838) 图像
特异性 This antibody recognizes endogenous levels of total Human Insulin protein.
交叉反应 (详细) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
纯化方法 Immunoaffinity Chromatography.
免疫原 INS antibody was raised against Synthetic peptide (KLH-coupled) derived from the sequence of Human Insulin.
亚型 IgG
Plasmids, Primers & others

Insulin目标详情

Insulin抗体详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN372838) 图像 回页首
抗原
别名 Insulin (INS Antibody 摘要)
背景 Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
基因ID 3630
NCBI登录号 NP_000198
UniProt P01308
途径 NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

使用细节

Insulin抗体详情 Insulin目标详情 贮存及处理 References for anti-Insulin antibody (ABIN372838) 图像 回页首
应用备注 ELISA. Flow Cytometry. Immunofluorescence. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Insulin抗体详情 Insulin目标详情 使用细节 References for anti-Insulin antibody (ABIN372838) 图像 回页首
状态 Liquid
浓度 0.02 mg/mL
缓冲液 10 mM HEPES, pH 7.5, 150 mM Sodium Chloride, 100 μg/mL BSA, 50 % Glycerol.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-Insulin antibody (ABIN372838)

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Micucci, Orciari, Catalano: "Hyperglycemia promotes K-Ras-induced lung tumorigenesis through BASCs amplification." in: PLoS ONE, Vol. 9, Issue 8, pp. e105550, 2014

Madsen, Knauf, Gotfredsen, Pilling, Sjögren, Andersen, Andersen, de Boer, Manova, Barlas, Vundavalli, Nyborg, Knudsen, Moelck, Fagin: "GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation." in: Endocrinology, Vol. 153, Issue 3, pp. 1538-47, 2012

"Retraction." in: Endocrinology, 2010

图像

Insulin抗体详情 Insulin目标详情 使用细节 贮存及处理 References for anti-Insulin antibody (ABIN372838) 回页首
厂商提供的图像
 image for anti-Insulin (INS) antibody (ABIN372838) anti-Insulin (INS) antibody