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Recombinant Insulin 抗体

INS 适用: 人, Pig, 小鼠, Cow, 兔 IHC, StM 宿主: 小鼠 Monoclonal rIRDN-805 unconjugated Recombinant Antibody
产品编号 ABIN6939797
发货至: 中国
  • 抗原 See all Insulin (INS) 抗体
    Insulin (INS)
    抗体类型
    Recombinant Antibody
    适用
    • 189
    • 105
    • 90
    • 75
    • 70
    • 39
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Pig, 小鼠, Cow, 兔
    宿主
    • 136
    • 86
    • 13
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 143
    • 98
    单克隆
    标记
    • 120
    • 20
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
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    • 4
    • 4
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    • 4
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    • 3
    • 3
    • 3
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    • 3
    • 2
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    • 1
    • 1
    This Insulin antibody is un-conjugated
    应用范围
    • 83
    • 74
    • 67
    • 67
    • 65
    • 55
    • 47
    • 39
    • 26
    • 24
    • 21
    • 17
    • 16
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    • 9
    • 9
    • 5
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    • 1
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    • 1
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    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length human Insulin protein
    克隆位点
    RIRDN-805
    亚型
    IgG1 kappa
    Top Product
    Discover our top product INS Primary Antibody
  • 应用备注

    Positive Control: MIA PaCa-2 cells. Pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Insulin (INS)
    别名
    INS (INS 产品)
    别名
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
    分子量
    6kDa
    基因ID
    3630
    UniProt
    P01308
    途径
    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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