INSIG1 抗体
(Insulin Induced Gene 1 (INSIG1))
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| INSIG1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (Internal Region) | 人, 小鼠 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 1-87) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 63-112) | 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, Pig, 猴, Hamster, 非洲爪蟾, Bat, 小鸡 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 71-120) | 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 绵羊, Pig, Hamster, 非洲爪蟾 | 兔 Polyclonal |
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| INSIG1 抗体 (C-Term) | 人, 猴 | 兔 Polyclonal |
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| INSIG1 抗体 (Middle Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| INSIG1 抗体 (Middle Region) | 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, 斑马鱼 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 2-85) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 36-63) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 36-63) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 1-87) (HRP) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 1-87) (Biotin) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 1-87) (FITC) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 36-63) (FITC) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 36-63) (APC) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (AA 36-63) (PE) | 人 | 兔 Polyclonal |
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| INSIG1 抗体 (N-Term) | 小鼠, 大鼠 | 兔 Polyclonal |
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| INSIG1 抗体 (Middle Region) | 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, Pig, 斑马鱼 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB21689
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 36-63, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-87
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, Pig, 猴, Hamster, 非洲爪蟾, Bat, 小鸡
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 63-112
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-85
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 36-63
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 36-63
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-87
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-87
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-87
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 36-63
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 36-63
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 36-63
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, Pig, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Latest Publications for our INSIG1 抗体
: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).
: "Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1561-7, (2013) (PubMed).
: "Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system." in: Acta physiologica (Oxford, England), Vol. 206, Issue 1, pp. 62-71, (2012) (PubMed).
: "Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin." in: Biochimie, Vol. 93, Issue 7, pp. 1165-71, (2011) (PubMed).
: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).
: "Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression." in: Molecular pharmacology, Vol. 73, Issue 4, pp. 1282-9, (2008) (PubMed).
: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).
: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).
: "Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1561-7, (2013) (PubMed).
: "Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system." in: Acta physiologica (Oxford, England), Vol. 206, Issue 1, pp. 62-71, (2012) (PubMed).
: "Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin." in: Biochimie, Vol. 93, Issue 7, pp. 1165-71, (2011) (PubMed).
: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).
: "Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression." in: Molecular pharmacology, Vol. 73, Issue 4, pp. 1282-9, (2008) (PubMed).
: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).
: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).
Aliases for INSIG1 抗体
insulin induced gene 1 (INSIG1) 抗体insulin induced gene 1 (insig1) 抗体
insulin induced gene 1 L homeolog (insig1.L) 抗体
insulin induced gene 1 (Insig1) 抗体
1810013C12Rik 抗体
cl-6 抗体
CL-6 抗体
cl6 抗体
CL6 抗体
fb55a03 抗体
fi35b10 抗体
Insig-1 抗体
INSIG-1 抗体
wu:fb55a03 抗体
wu:fi35b10 抗体
zgc:55439 抗体
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