The protein encoded by this gene represents the catalytic ATPase subunit of the INO80 chromatin remodeling complex. This complex binds DNA and is recruited by YY1 to activate certain genes.[provided by RefSeq, Apr 2010].
Yao, Song, Jin, Cai, Takahashi, Swanson, Washburn, Florens, Conaway, Cohen, Conaway: "Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex." in: Molecular cell, Vol. 31, Issue 6, pp. 909-17, (2008) (PubMed).