IRGM 产品
(Immunity-Related GTPase Family, M (IRGM))
Categories
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.[provided by RefSeq, Oct 2010].
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Featured IRGM Categories
Recommended IRGM 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN655080
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No.
ABIN752563
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN752565
Quantity
100 μL
Datasheet
Datasheet
Recommended IRGM 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7557606
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7548647
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN1098712
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our IRGM Products
: "Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. ..." in: Nature genetics, Vol. 40, Issue 6, pp. 710-2, (2008) (PubMed).: "Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease." in: Autophagy, Vol. 3, Issue 6, pp. 649-51, (2007) (PubMed).
: "Human IRGM induces autophagy to eliminate intracellular mycobacteria." in: Science (New York, N.Y.), Vol. 313, Issue 5792, pp. 1438-41, (2006) (PubMed).
: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).
Synonyms and alternative names related to IRGM
immunity-related GTPase family M member 1 (Irgm1), immunity-related GTPase M (Irgm), immunity related GTPase M (IRGM), immunity-related GTPase family M protein (LOC481473), Ifi1, IFI1, Iigp3, Iipg3, Irgm, IRGM1, LRG-47, LRG47Protein level used designations for IRGM
- LPS-stimulated RAW 264.7 macrophage protein 47
- immunity-related GTPase family M protein 1
- immunity-related GTPase family, M
- interferon inducible protein 1
- interferon-inducible GTPase 3
- interferon-inducible protein 1
- immunity-related GTPase family M protein
- LPS-stimulated RAW 264.7 macrophage protein 47 homolog
- LRG-47-like protein
- immunity-related GTPase family, M1
- immunity-related GTPase M
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