GIP 产品
(Gastric Inhibitory Polypeptide (GIP))
Categories
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
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Featured GIP Categories
GIP 抗体
High quality antibodies with extensive validation data.
GIP ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GIP 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GIP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7429760
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7129604
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN724850
Quantity
100 μL
Datasheet
Datasheet
Recommended GIP ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6956060
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6956059
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966966
Quantity
96 tests
Datasheet
Datasheet
Recommended GIP 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274747
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274746
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274749
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GIP Products
: "The Leading Role of Peptide Tyrosine Tyrosine in Glycemic Control After Roux-en-Y Gastric Bypass in Rats." in: Obesity surgery, Vol. 30, Issue 2, pp. 697-706, (2020) (PubMed).: "Low AS160 and high SGK basal phosphorylation associates with impaired incretin profile and type 2 diabetes in adipose tissue of obese patients." in: Diabetes research and clinical practice, Vol. 158, pp. 107928, (2020) (PubMed).
: "The Effects of Duodenojejunal Omega Switch in Combination with High-Fat Diet and Control Diet on Incretins, Body Weight, and Glucose Tolerance in Sprague-Dawley Rats." in: Obesity surgery, Vol. 28, Issue 3, pp. 748-759, (2018) (PubMed).
: "Regenerative Potential of Spermatogonial Stem Cells, Endothelial Progenitor Cells, and Epithelial Progenitor Cells of C57Bl/6 Male Mice with Metabolic Disorders." in: Bulletin of experimental biology and medicine, Vol. 163, Issue 2, pp. 239-244, (2018) (PubMed).
: "Pancreatic cancer-derived exosomes suppress the production of GIP and GLP-1 from STC-1���cells in vitro by down-regulating the PCSK1/3." in: Cancer letters, Vol. 431, pp. 190-200, (2018) (PubMed).
: "Preserving Duodenal-Jejunal (Foregut) Transit Does Not Impair Glucose Tolerance and Diabetes Remission Following Gastric Bypass in Type 2 Diabetes Sprague-Dawley Rat Model." in: Obesity surgery, Vol. 28, Issue 5, pp. 1313-1320, (2018) (PubMed).
: "A Dipeptidyl Peptidase-4 Inhibitor but not Incretins Suppresses Abdominal Aortic Aneurysms in Angiotensin II-Infused Apolipoprotein E-Null Mice." in: Journal of atherosclerosis and thrombosis, Vol. 23, Issue 4, pp. 441-54, (2017) (PubMed).
: "Novel GLP-1R/GIPR co-agonist "twincretin" is neuroprotective in cell and rodent models of mild traumatic brain injury." in: Experimental neurology, Vol. 288, pp. 176-186, (2017) (PubMed).
: "The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus." in: Scientific reports, Vol. 6, pp. 34284, (2016) (PubMed).
: "Specificity and promiscuity in human glutaminase interacting protein recognition: insight from the binding of the internal and C-terminal motif." in: Biochemistry, Vol. 51, Issue 35, pp. 6950-60, (2012) (PubMed).
Synonyms and alternative names related to GIP
gastric inhibitory polypeptide (GIP), gastric inhibitory polypeptide (gip), gastric inhibitory polypeptide (Gip), gastric inhibitory polypeptide L homeolog (gip.L), GIP, Gludins, RATGLUDINS, xgipProtein level used designations for GIP
- glucose-dependent insulinotropic polypeptide
- gastric inhibitory polypeptide
- incretin hormone
- Glucose-dependent insulinotropic peptide
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