GJA8 产品
(Gap Junction Protein, alpha 8, 50kDa (GJA8))
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This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009].
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Featured GJA8 Categories
Recommended GJA8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7153601
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN1774805
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN544553
Quantity
400 μL
Datasheet
Datasheet
Recommended GJA8 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355133
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355135
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3133561
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GJA8 Products
: "Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 11, pp. 4378-95, (2010) (PubMed).: "[A novel GJA8 mutation in a Chinese family with autosomal dominant congenital cataract]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 1, pp. 59-62, (2008) (PubMed).
: "A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1q." in: American journal of human genetics, Vol. 62, Issue 3, pp. 526-32, (1998) (PubMed).
: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 10, pp. 979-81, (1996) (PubMed).
: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 3, pp. 215-21, (1995) (PubMed).
Synonyms and alternative names related to GJA8
gap junction protein, alpha 8 (Gja8), gap junction protein alpha 8 (GJA8), Aey5, CAE, CAE1, Cnx50, CTRCT1, Cx45.6, Cx50, CX50, CZP1, Lop10, MP70Protein level used designations for GJA8
- alpha 8 connexin
- connexin-50
- gap junction alpha-8 protein
- gap junction membrane channel protein alpha 8
- lens fiber protein MP70
- lens opacity 10
- connexin 50
- cell surface glycoprotein
- gap junction membrane channel protein alpha-8
- lens intrinsic membrane protein MP70
- connexin 45.6
- connexin-45.6
- MP38
- MP64
- connexin-49
- cx49
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