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GIPR 产品

(Gastric Inhibitory Polypeptide Receptor (GIPR))
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011].

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Featured GIPR Categories

GIPR 抗体

High quality antibodies with extensive validation data.

GIPR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GIPR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GIPR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7153669
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6258423
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN391714
Quantity 400 μL
Datasheet Datasheet

Recommended GIPR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1134494
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5594084
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5594085
Quantity 96 tests
Datasheet Datasheet

Recommended GIPR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3121555
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3098320
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7491455
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GIPR Products

Ussher, Campbell, Mulvihill, Baggio, Bates, McLean, Gopal, Capozzi, Yusta, Cao, Ali, Kim, Kabir, Seino, Suzuki, Drucker: "Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).

Campbell, Ussher, Mulvihill, Kolic, Baggio, Cao, Liu, Lamont, Morii, Streutker, Tamarina, Philipson, Wrana, MacDonald, Drucker: "TCF1 links GIPR signaling to the control of beta cell function and survival." in: Nature medicine, Vol. 22, Issue 1, pp. 84-90, (2016) (PubMed).

Snook, Nelson, Dyck, Wright, Holloway: "Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 309, Issue 3, pp. R295-303, (2015) (PubMed).

Sparre-Ulrich, Hansen, Svendsen, Christensen, Knop, Hartmann, Holst, Rosenkilde: "Species-specific action of (Pro3)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors." in: British journal of pharmacology, Vol. 173, Issue 1, pp. 27-38, (2015) (PubMed).

Ugleholdt, Pedersen, Bassi, Füchtbauer, Jørgensen, Kissow, Nytofte, Poulsen, Rosenkilde, Seino, Thams, Holst, Holst: "Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain." in: The Journal of biological chemistry, Vol. 286, Issue 52, pp. 44632-45, (2011) (PubMed).

Figueiredo, Antunes, Moreira, de Mello, Medeiros, Di Giunta, Lobão-Soares, Linhares, Lin, Mazzuco, Prediger, Walz: "Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus." in: Peptides, Vol. 32, Issue 4, pp. 781-9, (2011) (PubMed).

Prasadan, Koizumi, Tulachan, Shiota, Lath, Paredes, Guo, El-Gohary, Malek, Shah, Gittes: "The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas." in: Diabetes, Vol. 60, Issue 2, pp. 548-54, (2011) (PubMed).

Kim, Nian, McIntosh: "Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation." in: Journal of lipid research, Vol. 52, Issue 4, pp. 759-70, (2011) (PubMed).

Gao, Coope, Grant, Ma, Ley, Harhaj: "ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling." in: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36592-602, (2011) (PubMed).

Synonyms and alternative names related to GIPR

gastric inhibitory polypeptide receptor (GIPR), glucagon receptor (LOC100303705), gastric inhibitory polypeptide receptor (Gipr), GIP-R, Gippr, GIPR, Gm160, Gm1081, PGQTL2, RATGIPPR

Protein level used designations for GIPR

  • gastric inhibitory polypeptide receptor
  • glucagon receptor
  • gastric inhibitory polypeptide receptor-like
  • GIP-R
  • glucose-dependent insulinotropic polypeptide receptor
  • gastric inhibitory peptide receptor
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