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GJB6 产品

(Gap Junction Protein, beta 6, 30kDa (GJB6))
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008].

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Featured GJB6 Categories

GJB6 抗体

High quality antibodies with extensive validation data.

GJB6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GJB6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GJB6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7000954
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7153625
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN357095
Quantity 0.4 mL
Datasheet Datasheet

Recommended GJB6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956054
Quantity 96 tests
Datasheet Datasheet

Recommended GJB6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355149
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415776
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111248
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GJB6 Products

Yu, Miao, Chen, Qi, Yang, Pan, Wang, Zhu: "Expressional and functional involvement of gap junctions in aqueous humor outflow into the ocular trabecular meshwork of the anterior chamber." in: Molecular vision, Vol. 25, pp. 255-265, (2019) (PubMed).

Berman, Carvallo, Buckner, Luers, Prevedel, Bennett, Eugenin: "HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS." in: Journal of neuroinflammation, Vol. 13, Issue 1, pp. 54, (2016) (PubMed).

Belguith, Tlili, Dhouib, Ben Rebeh, Lahmar, Charfeddine, Driss, Ghorbel, Ayadi, Masmoudi: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).

Beltramello, Bicego, Piazza, Ciubotaru, Mammano, DAndrea: "Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells." in: Biochemical and biophysical research communications, Vol. 305, Issue 4, pp. 1024-33, (2003) (PubMed).

Common, Becker, Di, Leigh, OToole, Kelsell: "Functional studies of human skin disease- and deafness-associated connexin 30 mutations." in: Biochemical and biophysical research communications, Vol. 298, Issue 5, pp. 651-6, (2002) (PubMed).

Smith, Morley, McLean: "A novel connexin 30 mutation in Clouston syndrome." in: The Journal of investigative dermatology, Vol. 118, Issue 3, pp. 530-2, (2002) (PubMed).

Synonyms and alternative names related to GJB6

connexin 30 (LOC387566), gap junction protein beta 2 (gjb2), gap junction protein beta 6 (GJB6), gap junction protein, beta 6 (Gjb6), AA958971, connexin-26, cx26, cx30, Cx30, CX30, CX31, D14Bwg0506e, dfna3, DFNA3, dfna3a, DFNA3B, dfnb1, dfnb1a, DFNB1B, ECTD2, ed2, ED2, edh, EDH, gjb6, hed, HED, HED2, nsrd1, ppk

Protein level used designations for GJB6

  • connexin 30
  • connexin 26
  • gap junction beta-2 protein
  • gap junction protein, beta 6, 30kDa
  • connexin-30
  • gap junction beta-6 protein
  • gap junction membrane channel protein beta 6
  • gap junction protein, beta 6 (connexin 30)
  • ectodermal dysplasia 2, hidrotic (Clouston syndrome)
  • connexin 31
  • connexin-31
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