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CDK4 蛋白

(Cyclin-Dependent Kinase 4 (CDK4))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

17 results :

CDK4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Pubmed 1 reference
产品编号 ABIN1348950
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
产品编号 ABIN7122532
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
产品编号 ABIN7122533
 
CDK4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1348948
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Imm
产品编号 ABIN7504963
 
CDK4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 80 % as determined by reducing SDS-PAGE.
产品编号 ABIN7195313
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7576064
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7393529
 
CDK4 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7403780
 
CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2128474
 
CDK4 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3009065
 
CDK4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713864
 
CDK4 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583816
 
CDK4 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583817
 
CDK4 宿主: 绵羊 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1476891
 
CDK4 宿主: Pig 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1472330
 
CDK4 宿主: 非洲爪蟾 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1614221
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Cow
    • Pig
    • Rat
    • Sheep
    • Xenopus laevis
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293 Cells
  • 抗原表位
    • AA 2-303
    • AA 1-303
    • AA 6-295
    • AA 1-319
    • AA 207-303
    • AA 211-303
  • 标记
    • His tag
    • GST tag
    • 非结合性
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • OriGene

Latest Publications for our CDK4 蛋白

Bockstaele, Kooken, Libert, Paternot, Dumont, de Launoit, Roger, Coulonval: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).

Aliases for CDK4 蛋白

cyclin-dependent kinase 4 (cdk4) 蛋白
cyclin dependent kinase 4 (CDK4) 蛋白
cyclin-dependent kinase 4 (Cdk4) 蛋白
cyclin dependent kinase 4 (Cdk4) 蛋白
Cyclin-dependent kinase 4 (Cdk4) 蛋白
cyclin-dependent kinase 4 L homeolog (cdk4.L) 蛋白
8-6 蛋白
cdk 蛋白
CDK4 蛋白
cdk4 蛋白
CDK4/6 蛋白
Cdk4/6 蛋白
cdk4/6 蛋白
CG5072 蛋白
CMM3 蛋白
Crk3 蛋白
dCdk4 蛋白
DmCdk4 蛋白
Dmel\\CG5072 蛋白
l(2)05428 蛋白
l(2)0671 蛋白
l(2)k06503 蛋白
l(2)s4639 蛋白
l(2)sh0671 蛋白
Pk53C 蛋白
Pk?7 蛋白
PSK-J3 蛋白
xcdk4 蛋白
zgc:153726 蛋白
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