CDK4 抗体
(Cyclin-Dependent Kinase 4 (CDK4))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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143 results :
CDK4
适用: 人, 小鼠, 大鼠
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
10 references
CDK4
适用: 人, 小鼠, 大鼠, 绵羊
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
2 references
CDK4
适用: 大鼠
WB, IF, IHC (p)
宿主: 兔
Polyclonal
unconjugated
1 reference
CDK4
适用: 人, 大鼠, 绵羊, Pig, 犬, Cow, 兔, 豚鼠, 马
WB, IHC
宿主: 兔
Polyclonal
unconjugated
CDK4
适用: 人
WB, ELISA, IP
宿主: 兔
Monoclonal
8F2
unconjugated
Recombinant Antibody
CDK4
适用: 人, 小鼠, 大鼠
WB, IF, FACS, ICC
宿主: 兔
Polyclonal
unconjugated
1 image
10 references
KD Validated
CDK4
适用: 人, 小鼠, 大鼠
WB, IP, IF, ICC
宿主: 兔
Monoclonal
unconjugated
Recombinant Antibody
Latest Publications for our CDK4 抗体
: "ASIC1a Inhibitor mambalgin-2 Suppresses the Growth of Leukemia Cells by Cell Cycle Arrest." in: Acta naturae, Vol. 12, Issue 2, pp. 101-116, (2020) (PubMed).: "Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway." in: International journal of molecular medicine, Vol. 44, Issue 5, pp. 1687-1696, (2020) (PubMed).
: "Regulation of miR-34b/c-targeted gene expression program by SUMOylation." in: Nucleic acids research, Vol. 46, Issue 14, pp. 7108-7123, (2019) (PubMed).
: "The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer." in: International journal of oncology, Vol. 51, Issue 5, pp. 1497-1507, (2018) (PubMed).
: "SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3115-3126, (2018) (PubMed).
: "Proteins of the retinoblastoma pathway, FEN1 and MGMT are novel potential prognostic biomarkers in pancreatic adenocarcinoma." in: Pathology, research and practice, Vol. 214, Issue 6, pp. 840-847, (2018) (PubMed).
: "Immune regulation mechanism of Astragaloside IV on RAW264.7 cells through activating the NF-κB/MAPK signaling pathway." in: International immunopharmacology, Vol. 49, pp. 38-49, (2018) (PubMed).
: "miR-3619-5p inhibits prostate cancer cell growth by activating CDKN1A expression." in: Oncology reports, Vol. 37, Issue 1, pp. 241-248, (2017) (PubMed).
: "Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 297-309, (2017) (PubMed).
: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).
Aliases for CDK4 抗体
cyclin-dependent kinase 4 (cdk4) 抗体cyclin dependent kinase 4 (CDK4) 抗体
cyclin-dependent kinase 4 (Cdk4) 抗体
cyclin dependent kinase 4 (Cdk4) 抗体
Cyclin-dependent kinase 4 (Cdk4) 抗体
cyclin-dependent kinase 4 L homeolog (cdk4.L) 抗体
8-6 抗体
cdk 抗体
CDK4 抗体
cdk4 抗体
CDK4/6 抗体
Cdk4/6 抗体
cdk4/6 抗体
CG5072 抗体
CMM3 抗体
Crk3 抗体
dCdk4 抗体
DmCdk4 抗体
Dmel\\CG5072 抗体
l(2)05428 抗体
l(2)0671 抗体
l(2)k06503 抗体
l(2)s4639 抗体
l(2)sh0671 抗体
Pk53C 抗体
Pk?7 抗体
PSK-J3 抗体
xcdk4 抗体
zgc:153726 抗体
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