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CDK4 抗体 (N-Term)

CDK4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7217934
发货至: 中国
  • 抗原 See all CDK4 抗体
    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
    抗原表位
    • 18
    • 16
    • 15
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 112
    • 72
    • 52
    • 19
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 103
    • 31
    • 2
    • 1
    克隆类型
    • 101
    • 35
    多克隆
    标记
    • 81
    • 10
    • 10
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK4 antibody is un-conjugated
    应用范围
    • 114
    • 49
    • 33
    • 27
    • 18
    • 18
    • 16
    • 15
    • 13
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Cdk4 Polyclonal Antibody
    特异性
    Cdk4 Polyclonal Antibody detects endogenous levels of Cdk4 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    免疫原
    Synthesized peptide derived from the N-terminal region of human Cdk4
    亚型
    IgG
    Top Product
    Discover our top product CDK4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
    别名
    Cdk4 (CDK4 产品)
    别名
    zgc:153726 antibody, CMM3 antibody, PSK-J3 antibody, Crk3 antibody, 8-6 antibody, CDK4 antibody, CDK4/6 antibody, CG5072 antibody, Cdk4/6 antibody, DmCdk4 antibody, Dmel\\CG5072 antibody, Pk53C antibody, Pk?7 antibody, cdk antibody, cdk4 antibody, cdk4/6 antibody, dCdk4 antibody, l(2)05428 antibody, l(2)0671 antibody, l(2)k06503 antibody, l(2)s4639 antibody, l(2)sh0671 antibody, xcdk4 antibody, cyclin-dependent kinase 4 antibody, cyclin dependent kinase 4 antibody, Cyclin-dependent kinase 4 antibody, cyclin-dependent kinase 4 L homeolog antibody, cdk4 antibody, CDK4 antibody, Cdk4 antibody, cdk4.L antibody
    背景
    Rabbit Anti-Cdk4 Polyclonal Antibody,CDK4, Cyclin-dependent kinase 4, Cell division protein kinase 4, PSK-J3,Cyclin-dependent kinase 4 encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16 (INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.,Cyclin-dependent kinase 4
    分子量
    observerd band 35kDa
    基因ID
    1019
    UniProt
    P11802
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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