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- 抗原 See all AXL 抗体
- AXL (AXL Receptor tyrosine Kinase (AXL))
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抗原表位
- Extracellular
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AXL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
- 克隆位点
- 7E10
- 亚型
- IgG1
- Top Product
- Discover our top product AXL Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours." in: British journal of cancer, Vol. 94, Issue 10, pp. 1446-51, (2006) (PubMed).
: "Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5799-804, (2006) (PubMed).
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Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours." in: British journal of cancer, Vol. 94, Issue 10, pp. 1446-51, (2006) (PubMed).
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- 抗原
- AXL (AXL Receptor tyrosine Kinase (AXL))
- 别名
- AXL (AXL 产品)
- 别名
- JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody
- 背景
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AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms: UFO, JTK11 - 分子量
- 97.4kDa
- 基因ID
- 558
- 途径
- RTK signaling, Cellular Response to Molecule of Bacterial Origin
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