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- 抗原 See all PRKAR2B 抗体
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
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抗原表位
- AA 118-147, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAR2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to PRKAR2B.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide between 118-147 amino acids from the Central region of human PRKAR2B
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PRKAR2B Primary Antibody
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anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) antibody
PRKAR2B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Ser113) antibodyPRKAR2B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Internal Region) antibodyPRKAR2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Ser113) antibodyPRKAR2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 32-62), (N-Term) antibodyPRKAR2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3253 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (pSer113) antibodyPRKAR2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (pSer113) antibodyPRKAR2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 304-413) antibodyPRKAR2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 1-418) antibodyPRKAR2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 32-62) antibodyPRKAR2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
- 别名
- PRKAR2B (PRKAR2B 产品)
- 别名
- MGC83177 antibody, PRKAR2B antibody, AI451071 antibody, AW061005 antibody, PKARIIbeta antibody, Pkarb2 antibody, RII(beta) antibody, RATDNA antibody, PRKAR2 antibody, RII-BETA antibody, protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog antibody, protein kinase cAMP-dependent type II regulatory subunit beta antibody, protein kinase, cAMP-dependent, regulatory, type II, beta antibody, protein kinase, cAMP dependent regulatory, type II beta antibody, protein kinase cAMP-dependent type 2 regulatory subunit beta antibody, prkar2b.S antibody, PRKAR2B antibody, prkar2b antibody, Prkar2b antibody
- 背景
- CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq].Synonyms: PRKAR2, cAMP-dependent protein kinase type II-beta regulatory subunit
- 分子量
- 46302 Da
- 基因ID
- 5577
- NCBI登录号
- NP_002727
- 途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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