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- 抗原 See all PRKAR2B 抗体
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PRKAR2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- PRKAR2B Rabbit mAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human PRKAR2B
- 亚型
- IgG
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anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Ser113) antibody
PRKAR2B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Internal Region) antibodyPRKAR2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (Ser113) antibodyPRKAR2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 32-62), (N-Term) antibodyPRKAR2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3253 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (pSer113) antibodyPRKAR2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (pSer113) antibodyPRKAR2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 304-413) antibodyPRKAR2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 1-418) antibodyPRKAR2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (AA 32-62) antibodyPRKAR2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B) (pSer113) antibodyPRKAR2B 适用: 人, 小鼠, 大鼠, 猴, 兔 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))
- 别名
- PRKAR2B (PRKAR2B 产品)
- 别名
- MGC83177 antibody, PRKAR2B antibody, AI451071 antibody, AW061005 antibody, PKARIIbeta antibody, Pkarb2 antibody, RII(beta) antibody, RATDNA antibody, PRKAR2 antibody, RII-BETA antibody, protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog antibody, protein kinase cAMP-dependent type II regulatory subunit beta antibody, protein kinase, cAMP-dependent, regulatory, type II, beta antibody, protein kinase, cAMP dependent regulatory, type II beta antibody, protein kinase cAMP-dependent type 2 regulatory subunit beta antibody, prkar2b.S antibody, PRKAR2B antibody, prkar2b antibody, Prkar2b antibody
- 背景
- CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008],PRKAR2, RII-BETA,Apoptosis,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Insulin Receptor Signaling Pathway,Kinase,Lipid Metabolism,MAPK-Erk Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Signal Transduction,PRKAR2B
- 分子量
- 46kDa
- 基因ID
- 5577
- UniProt
- P31323
- 途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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