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TANK 抗体 (AA 151-260) (Alexa Fluor 488)

TANK 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN917117
发货至: 中国
  • 抗原 See all TANK 抗体
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-260
    适用
    • 55
    • 14
    • 12
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 53
    • 1
    • 1
    • 1
    克隆类型
    • 56
    多克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TANK antibody is conjugated to Alexa Fluor 488
    应用范围
    • 37
    • 26
    • 18
    • 13
    • 12
    • 12
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TANK
    亚型
    IgG
    Top Product
    Discover our top product TANK Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    别名
    TANK (TANK 产品)
    别名
    I-TRAF antibody, ITRAF antibody, TRAF2 antibody, C86182 antibody, E430026L09Rik antibody, zgc:153048 antibody, i-traf antibody, tank antibody, traf2 antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated Nf-kappa B activator antibody, TRAF family member-associated NFKB activator antibody, TRAF family member associated NFKB activator L homeolog antibody, TANK antibody, Tank antibody, tank antibody, tank.L antibody
    背景

    Synonyms: I TRAF, ITRAF, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein, TRAF interacting protein TANK isoform a, I-TRAF, Tank, TANK_HUMAN, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF interacting protein TANK isoform b, TRAF2.

    Background: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.

    基因ID
    10010
    途径
    p53 Pathway, TLR signaling, Activation of Innate immune Response
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