CHEK1 抗体 (AA 1-210) (FITC)
Our Local Distributor
北京 101111
Quick Overview for CHEK1 抗体 (AA 1-210) (FITC) (ABIN7978348)
抗原
See all CHEK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-210
-
原理
- Anti-Chk1/CHEK1 Antibody FITC Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
预测反应
- Human Chk1 shares 96.7%,97.6% amino acid (aa) sequence identity with mouse,rat Chk1,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Chk1 recombinant protein (Position: M1-Q210). Human Chk1 shares 96.7% and 97.6% amino acid (aa) sequence identity with mouse and rat Chk1, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
-
别名
- CHEK1
-
背景
-
Background: CHEK1, Cell cycle checkpoint kinase, is an enzyme that in humans is encoded by the CHEK1 gene. By fluorescence in situ hybridization, the human CHEK1 gene is mapped to 11q24, near the ATM gene at 11q23. CHEK1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Furthermore, CHEK1 acts to integrate signals from ATM and ATR, and is involved in monitoring meiotic recombination, a process that involves programmed DNA breaks.
Gene Full Name: checkpoint kinase 1
-
基因ID
- 1111
-
UniProt
- O14757
-
途径
- p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
抗原
-