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IL1R2 抗体 (AA 301-398)

IL1R2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN747758
发货至: 中国
  • 抗原 See all IL1R2 抗体
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    抗原表位
    • 15
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-398
    适用
    • 70
    • 26
    • 19
    • 4
    人, 小鼠, 大鼠
    宿主
    • 49
    • 22
    • 1
    • 1
    克隆类型
    • 51
    • 21
    多克隆
    标记
    • 40
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1R2 antibody is un-conjugated
    应用范围
    • 60
    • 32
    • 29
    • 12
    • 12
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IL-1R II
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    别名
    IL-1R2 (IL1R2 产品)
    别名
    CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
    背景

    Synonyms: IL1RB, CD121b, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2, Interleukin-1 receptor type 2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, IL1R2

    Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

    基因ID
    7850
    UniProt
    P27930
    途径
    NF-kappaB Signaling
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