Recombinant IL1R2 抗体 (Extracellular Domain)
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- 抗原 See all IL1R2 抗体
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- 抗体类型
- Recombinant Antibody
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抗原表位
- Extracellular Domain
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL1R2 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 特异性
- Recognizes mouse IL-1R2.
- 交叉反应
- 小鼠
- 纯化方法
- Purified from HEK 293 cell culture supernatant.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL-test, Lonza).
- 免疫原
- Recombinant mouse IL-1R2 (extracellular domain).
- 克隆位点
- Praxy-1-1
- 亚型
- IgG2b
- Top Product
- Discover our top product IL1R2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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IL-1R2 (mouse) monoclonal antibody (recombinant) (Praxy-1-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse IgG2b Fc domain.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- 别名
- IL-1R2 (IL1R2 产品)
- 别名
- CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
- 背景
- The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
- UniProt
- P27931
- 途径
- NF-kappaB Signaling
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