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IL1R2 抗体

IL1R2 适用: 人 IA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2192180
发货至: 中国
  • 抗原 See all IL1R2 抗体
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    适用
    • 70
    • 27
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    宿主
    • 49
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    克隆类型
    • 51
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    多克隆
    标记
    • 40
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    This IL1R2 antibody is un-conjugated
    应用范围
    • 61
    • 33
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    Immunoassay (IA)
    过滤
    0.2 μm filtered
    Top Product
    Discover our top product IL1R2 Primary Antibody
  • 应用备注
    For immuno assays dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Mantovani, Muzio, Ghezzi, Colotta, Introna: "Regulation of inhibitory pathways of the interleukin-1 system." in: Annals of the New York Academy of Sciences, Vol. 840, pp. 338-51, (1998) (PubMed).

  • 抗原
    IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
    Abstract
    IL1R2 产品
    别名
    CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
    背景
    The antibody reacts specificly with human Interleukin (IL-1) R II. The IL-1 system includes two agonists (IL- 1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 R I and IL-1 R II) and the IL-1 receptor accessory protein. The IL-1 R II is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signalling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1 R I. The decoy IL-1 R II can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1 R II exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
    途径
    NF-kappaB Signaling
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