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UPF3B 抗体 (AA 1-180)

UPF3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7271228
发货至: 中国
  • 抗原 See all UPF3B 抗体
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-180
    适用
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    原理
    UPF3B Rabbit pAb
    序列
    MKEEKEHRPK EKRVTLLTPA GATGSGGGTS GDSSKGEDKQ DRNKEKKEAL SKVVIRRLPP TLTKEQLQEH LQPMPEHDYF EFFSNDTSLY PHMYARAYIN FKNQEDIILF RDRFDGYVFL DNKGQEYPAI VEFAPFQKAA KKKTKKRDTK VGTIDDDPEY RKFLESYATD NEKMTSTPET
    交叉反应
    小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human UPF3B (NP_075386.1).
    亚型
    IgG
    Top Product
    Discover our top product UPF3B Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    别名
    UPF3B (UPF3B 产品)
    别名
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    背景
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.,UPF3B,HUPF3B,MRX62,MRXS14,RENT3B,UPF3BP1,UPF3BP2,UPF3BP3,UPF3X,Upf3p-X,Epigenetics & Nuclear Signaling,RNA Binding,UPF3B
    分子量
    56kDa/57kDa
    基因ID
    65109
    UniProt
    Q9BZI7
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