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UPF3B 抗体 (AA 300-350)

UPF3B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7450880
发货至: 中国
  • 抗原 See all UPF3B 抗体
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-350
    适用
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-UPF3B Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 300 and 350
    亚型
    IgG
    Top Product
    Discover our top product UPF3B Primary Antibody
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    别名
    UPF3B (UPF3B 产品)
    别名
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    背景
    Background: UPF3B (UPF regulator of nonsense transcripts homolog B) is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. UPF3B recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2, UPF3B stimulates both ATPase and RNA helicase activities of UPF1 [taken from the Universal Protein Resource (UniProt) Q9BZI7].
    基因ID
    65109
    NCBI登录号
    NP_542199
    UniProt
    Q9BZI7
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