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UPF3B 抗体

UPF3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120629
发货至: 中国
  • 抗原 See all UPF3B 抗体
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    适用
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    应用范围
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    UPF3 regulator of nonsense transcripts homolog B(yeast)
    亚型
    IgG
    Top Product
    Discover our top product UPF3B Primary Antibody
  • 应用备注
    WB: 1:500-1:5000, IHC:1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    别名
    UPF3B (UPF3B 产品)
    别名
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    背景
    Synonyms:HUPF3B, hUpf3p X, MRXS14, RENT3B, UPF3B, UPF3X Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core.
    分子量
    58 kDa
    基因ID
    65109
    UniProt
    Q9BZI7
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