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GCH1 抗体 (AA 1-250)

GCH1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267525
发货至: 中国
  • 抗原 See all GCH1 抗体
    GCH1 (GTP Cyclohydrolase 1 (GCH1))
    抗原表位
    • 15
    • 11
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1-250
    适用
    • 39
    • 24
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 47
    • 7
    • 1
    克隆类型
    • 52
    • 3
    多克隆
    标记
    • 21
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCH1 antibody is un-conjugated
    应用范围
    • 46
    • 29
    • 18
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    GCH1 Rabbit pAb
    序列
    MEKGPVRAPA EKPRGARCSN GFPERDPPRP GPSRPAEKPP RPEAKSAQPA DGWKGERPRS EEDNELNLPN LAAAYSSILS SLGENPQRQG LLKTPWRAAS AMQFFTKGYQ ETISDVLNDA IFDEDHDEMV IVKDIDMFSM CEHHLVPFVG KVHIGYLPNK QVLGLSKLAR IVEIYSRRLQ VQERLTKQIA VAITEALRPA GVGVVVEATH MCMVMRGVQK MNSKTVTSTM LGVFREDPKT REEFLTLIRS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GCH1 (NP_000152.1).
    亚型
    IgG
    Top Product
    Discover our top product GCH1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GCH1 (GTP Cyclohydrolase 1 (GCH1))
    别名
    GCH1 (GCH1 产品)
    别名
    DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH antibody, GTP-CH-1 antibody, GTPCH1 antibody, HPABH4B antibody, GTP-CH antibody, GTPCH antibody, Gch antibody, MGC89622 antibody, gch1a antibody, wu:fc16b10 antibody, zgc:195269 antibody, GTP cyclohydrolase 1 antibody, GTP cyclohydrolase 1-like antibody, GCH1 antibody, Gch1 antibody, gch1 antibody, Weevi_1190 antibody, Halhy_0838 antibody, Sinme_1220 antibody, Sphch_1077 antibody, LOC100136794 antibody
    背景
    This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.,GCH1,DYT14,DYT5,DYT5a,GCH,GTP-CH-1,GTPCH1,HPABH4B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,GCH1
    分子量
    23kDa/25kDa/27kDa
    基因ID
    2643
    UniProt
    P30793
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