IL1R2 抗体 (AA 14-343)
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- 抗原 See all IL1R2 抗体
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
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抗原表位
- AA 14-343
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL1R2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.
- 克隆位点
- 5D7B1
- 亚型
- IgG1
- Top Product
- Discover our top product IL1R2 Primary Antibody
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- 应用备注
- WB:1:500 - 1:2000, ICC:1:50 - 1:200, FCM:1:200 - 1:400, ELISA:1:10000,
- 限制
- 仅限研究用
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- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- 别名
- CD121B (IL1R2 产品)
- 别名
- CD121b antibody, CDw121b antibody, IL-1R-2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R2c antibody, IL1RB antibody, Il1r-2 antibody, IL-1R2 antibody, interleukin 1 receptor type 2 antibody, interleukin 1 receptor, type II antibody, interleukin-like antibody, IL1R2 antibody, Il1r2 antibody, KK34 antibody
- 背景
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Description: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Aliases: IL1R2,IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
- 分子量
- 45.4 kDa
- 基因ID
- 7850
- 途径
- NF-kappaB Signaling
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