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MDM2 抗体 (AA 26-169)

MDM2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4A8D12 unconjugated
产品编号 ABIN7193592
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    抗原表位
    • 26
    • 25
    • 14
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 4
    • 4
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    • 2
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    • 1
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    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 26-169
    适用
    • 193
    • 79
    • 54
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 169
    • 27
    • 1
    小鼠
    克隆类型
    • 169
    • 28
    单克隆
    标记
    • 99
    • 13
    • 9
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    • 7
    • 6
    • 6
    • 6
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    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MDM2 antibody is un-conjugated
    应用范围
    • 124
    • 76
    • 63
    • 38
    • 29
    • 27
    • 27
    • 18
    • 17
    • 14
    • 10
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    • 1
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. coli.
    克隆位点
    4A8D12
    亚型
    IgG1
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注
    WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    别名
    ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
    背景

    Description: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]

    Aliases: HDMX, LSKB, hdm2, ACTFS

    分子量
    55.2 kDa
    基因ID
    4193
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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