JMY 抗体 (AA 708-848) (HRP)
-
- 抗原 See all JMY 抗体
- JMY (Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
-
抗原表位
- AA 708-848
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This JMY antibody is conjugated to HRP
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Junction-mediating and -regulatory protein (708-848AA)
- 亚型
- IgG
- Top Product
- Discover our top product JMY Primary Antibody
-
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibody
JMY 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibodyJMY 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 708-848) antibodyJMY 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 2-29), (N-Term) antibodyJMY 适用: 人 WB 宿主: 兔 Polyclonal RB30560 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibodyJMY 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 401-500) antibodyJMY 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠, Cow, 犬, 小鸡, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- JMY (Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
- 别名
- JMY (JMY 产品)
- 别名
- WHDC1L3 antibody, junction mediating and regulatory protein, p53 cofactor antibody, junction-mediating and regulatory protein antibody, JMY antibody, jmy antibody, Jmy antibody
- 背景
-
Background: Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity).
Aliases: FLJ37870 antibody, Jmy antibody, JMY protein antibody, JMY_HUMAN antibody, junction mediating and regulatory protein antibody, Junction mediating and regulatory protein p53 cofactor antibody, Junction-mediating and -regulatory protein antibody, MGC163496 antibody, OTTHUMP00000161976 antibody, WAS protein homology region 2 domain containing 1-like 3 antibody, WHDC1L3 antibody
- UniProt
- Q8N9B5
- 途径
- Regulation of Actin Filament Polymerization
-
