JMY 抗体
(Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.
recommended
recommended
recommended
JMY 抗体 by 适用
Find JMY 抗体 for a variety of species such as anti-Human JMY, anti-Mouse JMY, anti-Cow JMY. The species listed below are among those available. Click on a link to go to the corresponding products.
JMY 抗体 by 应用范围
Find JMY 抗体 validated for a specific application such as WB, ELISA, IF, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
JMY 抗体 by 抗体来源
Find JMY 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
JMY 抗体 by 克隆形成能力
Find available monoclonal or polyclonal JMY 抗体. Click on a link to go to the corresponding products.
JMY 抗体 by 克隆
Find JMY 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
JMY 抗体 by 标记
Find JMY 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular JMY 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (4)
Cat. No.
ABIN530707
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF, ELISA, WB
Validations
- (3)
Cat. No.
ABIN530706
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (2)
Cat. No.
ABIN7157162
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, ICC, IF, WB
Validations
- (2)
Cat. No.
ABIN6262708
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881469
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Pig
Application
IHC, WB
Validations
- (2)
Cat. No.
ABIN7300900
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN530705
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN7185068
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
- (1)
Cat. No.
ABIN872348
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN3185267
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN1533471
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN1577400
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN2789961
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
Cat. No.
ABIN2686673
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7157165
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our JMY 抗体
: "A transcription co-factor integrates cell adhesion and motility with the p53 response." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 47, pp. 19872-7, (2009) (PubMed).: "p53-cofactor JMY is a multifunctional actin nucleation factor." in: Nature cell biology, Vol. 11, Issue 4, pp. 451-9, (2009) (PubMed).
: "Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients." in: Genes, chromosomes & cancer, Vol. 47, Issue 8, pp. 680-96, (2008) (PubMed).
: "Mdm2 targets the p53 transcription cofactor JMY for degradation." in: EMBO reports, Vol. 8, Issue 1, pp. 84-90, (2007) (PubMed).
: "A novel cofactor for p300 that regulates the p53 response." in: Molecular cell, Vol. 4, Issue 3, pp. 365-76, (1999) (PubMed).
Aliases for JMY 抗体
junction mediating and regulatory protein, p53 cofactor (JMY) 抗体junction mediating and regulatory protein, p53 cofactor (jmy) 抗体
junction-mediating and regulatory protein (Jmy) 抗体
WHDC1L3 抗体
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