JMY 抗体 (AA 401-500)
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- 抗原 See all JMY 抗体
- JMY (Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
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抗原表位
- AA 401-500
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JMY antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human JMY
- 亚型
- IgG
- Top Product
- Discover our top product JMY Primary Antibody
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anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibody
JMY 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibodyJMY 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 708-848) antibodyJMY 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 2-29), (N-Term) antibodyJMY 适用: 人 WB 宿主: 兔 Polyclonal RB30560 unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (AA 535-634) antibodyJMY 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) (C-Term) antibodyJMY 适用: 人, 小鼠, Cow, 犬, 小鸡, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- JMY (Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
- 别名
- JMY (JMY 产品)
- 背景
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Synonyms: WHAMM2, WHDC1L3, Junction-mediating and -regulatory protein, JMY
Background: Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity).
- 基因ID
- 133746
- UniProt
- Q8N9B5
- 途径
- Regulation of Actin Filament Polymerization
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