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MAP2K7 抗体 (pThr275)

MAP2K7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138822
发货至: 中国
  • 抗原 See all MAP2K7 抗体
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    抗原表位
    • 25
    • 25
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr275
    适用
    • 84
    • 54
    • 45
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 81
    • 6
    克隆类型
    • 67
    • 20
    多克隆
    标记
    • 47
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP2K7 antibody is un-conjugated
    应用范围
    • 70
    • 35
    • 24
    • 23
    • 15
    • 14
    • 13
    • 11
    • 7
    • 6
    • 5
    • 1
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of threonine 275(A-K-T(p)-R-S) derived from Human MAP2K7.
    亚型
    IgG
    Top Product
    Discover our top product MAP2K7 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    别名
    MAP2K7 (MAP2K7 产品)
    别名
    MAP2K7 antibody, 2 antibody, JNKK antibody, Jnkk2 antibody, Mapkk7 antibody, Mek7 antibody, Mkk7 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, SAPKK-4 antibody, SAPKK4 antibody, 5930412N11Rik antibody, JNKK 2 antibody, MAPKK 7 antibody, MEK 7 antibody, Prkmk7 antibody, sek2 antibody, si:ch211-254d18.2 antibody, map2k7-A antibody, mitogen-activated protein kinase kinase 7 antibody, mitogen activated protein kinase kinase 7 antibody, mitogen-activated protein kinase kinase 7 L homeolog antibody, MAP2K7 antibody, Map2k7 antibody, map2k7 antibody, map2k7.L antibody
    背景

    Background:

    The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

    Wu Z.,Mol. Cell. Biol. 17:7407-7416(1997).
    Lu X.,J. Biol. Chem. 272:24751-24754(1997).
    The MGC Project Team,Genome Res. 14:2121-2127(2004).

    Aliases: c-Jun N-terminal kinase kinase 2 antibody, Dual specificity mitogen activated protein kinase kinase 7 antibody, Dual specificity mitogen-activated protein kinase kinase 7 antibody, JNK activating kinase 2 antibody, JNK kinase 2 antibody, JNK-activating kinase 2 antibody, JNKK 2 antibody, Jnkk-2 antibody, Jnkk2 antibody, MAP kinase kinase 7 antibody, MAP2K7 antibody, MAPK/ERK kinase 7 antibody, MAPKK 7 antibody, MAPKK-7 antibody, MAPKK7 antibody, MEK 7 antibody, Mitogen Activated Protein Kinase kinase 7 antibody, MKK 7 antibody, MKK-7 antibody, MKK7 antibody, MP2K7_HUMAN antibody, PRKMK 7 antibody, PRKMK-7 antibody, PRKMK7 antibody, SAPK kinase 4 antibody, SAPKK-4 antibody, SAPKK4 antibody, Sek 2 antibody, Sek-2 antibody, Sek2 antibody, SKK4 antibody, stress-activated protein kinase kinase 4 antibody

    UniProt
    O14733
    途径
    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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