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MAP2K7 抗体

MAP2K7 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4-00E-05 unconjugated
产品编号 ABIN969271
发货至: 中国
  • 抗原 See all MAP2K7 抗体
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    适用
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    宿主
    • 82
    • 5
    小鼠
    克隆类型
    • 68
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    单克隆
    标记
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    This MAP2K7 antibody is un-conjugated
    应用范围
    • 70
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human MAP2K7 expressed in E. coli.
    克隆位点
    4-00E-05
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Nakagawa, Sugahara, Yamasaki, Kajiho, Takahashi, Hirayama, Minami, Ohta, Watanabe, Hata, Katada, Nishina: "Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation." in: The Biochemical journal, Vol. 427, Issue 2, pp. 237-45, (2010) (PubMed).

    Yoshizawa, Hammaker, Sweeney, Boyle, Firestein: "Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3252-8, (2008) (PubMed).

  • 抗原
    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
    别名
    MAP2K7 (MAP2K7 产品)
    别名
    MAP2K7 antibody, 2 antibody, JNKK antibody, Jnkk2 antibody, Mapkk7 antibody, Mek7 antibody, Mkk7 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, SAPKK-4 antibody, SAPKK4 antibody, 5930412N11Rik antibody, JNKK 2 antibody, MAPKK 7 antibody, MEK 7 antibody, Prkmk7 antibody, sek2 antibody, si:ch211-254d18.2 antibody, map2k7-A antibody, mitogen-activated protein kinase kinase 7 antibody, mitogen activated protein kinase kinase 7 antibody, mitogen-activated protein kinase kinase 7 L homeolog antibody, MAP2K7 antibody, Map2k7 antibody, map2k7 antibody, map2k7.L antibody
    背景

    Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

    Aliases: MKK7, Jnkk2, MAPKK7, PRKMK7

    分子量
    48 kDa
    基因ID
    5609
    HGNC
    5609
    途径
    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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