Recombinant NPC1L1 抗体
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- 抗原 See all NPC1L1 抗体
- NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This NPC1L1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Affinity-chromatography
- 免疫原
- A synthesized peptide derived from human NPC1L1
- 克隆位点
- 4B10
- 亚型
- IgG
- Top Product
- Discover our top product NPC1L1 Primary Antibody
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anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 500-600) antibody
NPC1L1 适用: 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 294-323), (N-Term) antibodyNPC1L1 适用: 人 WB 宿主: 兔 Polyclonal RB42754 unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 1000-1100) antibodyNPC1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 596-610) antibodyNPC1L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (N-Term) antibodyNPC1L1 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 1030-1100) antibodyNPC1L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))
- 别名
- NPC1L1 (NPC1L1 产品)
- 别名
- NPC1L1 antibody, 9130221N23Rik antibody, Gm243 antibody, NPC11L1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, NPC1 like 1 antibody, NPC1-like 1 antibody, NPC1L1 antibody, npc1l1 antibody, Npc1l1 antibody
- 背景
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Background: Plays a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption. Lack of activity leads to multiple lipid transport defects. The protein may have a function in the transport of multiple lipids and their homeostasis, and may play a critical role in regulating lipid metabolism. Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation.
Aliases: NPC1-like intracellular cholesterol transporter 1 (Niemann-Pick C1-like protein 1), NPC1L1
- UniProt
- Q9UHC9
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