-
- 抗原 See all NPC1L1 抗体
- NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))
-
抗原表位
- AA 1030-1100
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NPC1L1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- AAYSTSVNLT SDGQVLASRF MAYHKPLKNS QDYTEALRAA RELAANITAD LRKVPGTDPA FEVFPYTITN V
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1030-1100 of human NPC1L1 (NP_001095118.1).
- 亚型
- IgG
- Top Product
- Discover our top product NPC1L1 Primary Antibody
-
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 500-600) antibody
NPC1L1 适用: 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 294-323), (N-Term) antibodyNPC1L1 适用: 人 WB 宿主: 兔 Polyclonal RB42754 unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 1000-1100) antibodyNPC1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) antibodyNPC1L1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 4B10 unconjugated Recombinant Antibody
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (AA 596-610) antibodyNPC1L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1) (N-Term) antibodyNPC1L1 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB,1:1000 - 1:4000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- NPC1L1 (NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))
- 别名
- NPC1L1 (NPC1L1 产品)
- 别名
- NPC1L1 antibody, 9130221N23Rik antibody, Gm243 antibody, NPC11L1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, NPC1 like 1 antibody, NPC1-like 1 antibody, NPC1L1 antibody, npc1l1 antibody, Npc1l1 antibody
- 背景
- The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up free cholesterol into cells through vesicular endocytosis and plays a critical role in the absorption of intestinal cholesterol. It also has the ability to transport alpha-tocopherol (vitamin E). The drug ezetimibe targets this protein and inhibits the absorption of intestinal cholesterol and alpha-tocopherol. In addition, this protein may play a critical role in regulating lipid metabolism. Polymorphic variations in this gene are associated with plasma total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) risk. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,NPC1L1,NPC11L1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,NPC1L1
- 分子量
- 79 kDa/140 kDa/145 kDa/148 kDa
- 基因ID
- 29881
- UniProt
- Q9UHC9
-
You are here:
