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ERCC2 抗体
ERCC2
适用: 人
WB, ELISA, IHC, IP
宿主: 兔
Polyclonal
unconjugated
ERCC2抗体详情
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抗原
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ERCC2
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
适用
All reactivities for ERCC2 抗体
人
宿主
All hosts for ERCC2 抗体
兔
克隆类型
All clonalities for ERCC2 抗体
多克隆
标记
All conjugates for ERCC2 抗体
This ERCC2 antibody is un-conjugated
应用范围
All applications for ERCC2 抗体
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
纯化方法
Immunogen affinity purified
纯度
≥95 % as determined by SDS-PAGE
免疫原
excision repair cross-complementing rodent repair deficiency, complementation group 2
亚型
IgG
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使用细节
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应用备注
WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
ERCC2目标详情
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抗原
ERCC2
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
别名
ERCC2 (ERCC2 产品 )
别名
COFS2 antibody, EM9 antibody, TTD antibody, XPD antibody, AA407812 antibody, AU020867 antibody, AW240756 antibody, CXPD antibody, Ercc-2 antibody, MGC89573 antibody, CG9433 antibody, DhR3 antibody, DhXPD antibody, DmXPD antibody, Dmel\\CG9433 antibody, ERCC2 antibody, XPD/ERCC2 antibody, l(2)SH2 2137 antibody, l(2)SH2137 antibody, xpd antibody, zgc:56365 antibody, ERCC excision repair 2, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 2 antibody, excision repair cross-complementation group 2 antibody, Xeroderma pigmentosum D antibody, ERCC2 antibody, Ercc2 antibody, ercc2 antibody, Xpd antibody
背景
Synonyms:XPD, XPDC Background:ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
分子量
80 kDa
基因ID
2068
UniProt
P18074
途径
DNA Damage Repair
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