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AATF 抗体

AATF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111679
发货至: 中国
  • 抗原 See all AATF 抗体
    AATF (Apoptosis Antagonizing Transcription Factor (AATF))
    适用
    • 45
    • 14
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 3
    • 1
    克隆类型
    • 43
    • 4
    多克隆
    标记
    • 34
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AATF antibody is un-conjugated
    应用范围
    • 34
    • 20
    • 12
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    apoptosis antagonizing transcription factor
    亚型
    IgG
    Top Product
    Discover our top product AATF Primary Antibody
  • 应用备注
    WB: 1:200-1:2000, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    AATF (Apoptosis Antagonizing Transcription Factor (AATF))
    别名
    AATF (AATF 产品)
    别名
    AATF antibody, ded antibody, che1 antibody, che-1 antibody, cb109 antibody, sb:cb109 antibody, wu:fc13d05 antibody, zgc:162071 antibody, CHE-1 antibody, CHE1 antibody, DED antibody, 4933415H02Rik antibody, 5830465M17Rik antibody, Che-1 antibody, Trb antibody, Ded antibody, apoptosis antagonizing transcription factor antibody, Apoptosis antagonizing transcription factor antibody, apoptosis antagonizing transcription factor S homeolog antibody, AATF antibody, aatf antibody, BFR2 antibody, NAEGRDRAFT_56916 antibody, Aatf antibody, aatf.S antibody
    背景
    Synonyms:AATF, CHE 1, CHE1, DED, Protein AATF, Rb binding protein Che 1, Traube Background:May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease(presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
    分子量
    63 kDa
    基因ID
    26574
    UniProt
    Q9NY61
    途径
    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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