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AATF 抗体 (N-Term)

Name: AATF 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN7184406
Availability: OutOfStock

AATF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from HeLa cells, HepG2 cells, COLO205 cells and HUVEC cells, using AATF antibody. (AATF 抗体 (N-Term))

1 image

产品编号 ABIN7184406

发货至: 中国

Datasheet as PDF

抗原 See all AATF 抗体

AATF (Apoptosis Antagonizing Transcription Factor (AATF))
抗原表位
8

6

4

2

2

2

1

1

1

1

1

1

1

1

1
N-Term
适用
45

15

11

5

4

4

4

4

3

2

2

2

1
人
宿主
43

3

1
兔
Compatible Secondaries
克隆类型
43

4
多克隆
标记
34

3

2

2

1

1

1

1

1

1
This AATF antibody is un-conjugated
应用范围
34

20

12

8

6

6

5

1

1

1

1

1

1
Western Blotting (WB), ELISA

交叉反应

人, 小鼠, 大鼠

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

免疫原

Synthesized peptide derived from N-terminal of Human AATF.

亚型

IgG

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anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibody
AATF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 451-560) antibody
AATF 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 1-39) antibody
AATF 适用: 人, 小鼠 WB, IF 宿主: 大鼠 Monoclonal 1B2D8 unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 240-438) antibody
AATF 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 237-523) antibody
AATF 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibody
AATF 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibody
AATF 适用: 人, 猴 WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibody
AATF 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 6-294) antibody
AATF 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:3000,

限制

仅限研究用
状态

Liquid

缓冲液

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

AATF (Apoptosis Antagonizing Transcription Factor (AATF))

别名

AATF (AATF 产品)

别名

AATF antibody, ded antibody, che1 antibody, che-1 antibody, cb109 antibody, sb:cb109 antibody, wu:fc13d05 antibody, zgc:162071 antibody, CHE-1 antibody, CHE1 antibody, DED antibody, 4933415H02Rik antibody, 5830465M17Rik antibody, Che-1 antibody, Trb antibody, Ded antibody, apoptosis antagonizing transcription factor antibody, Apoptosis antagonizing transcription factor antibody, apoptosis antagonizing transcription factor S homeolog antibody, AATF antibody, aatf antibody, BFR2 antibody, NAEGRDRAFT_56916 antibody, Aatf antibody, aatf.S antibody

背景

Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.

Lindfors K., Biochem. Biophys. Res. Commun. 276:660-666(2000).
Fanciulli M., FASEB J. 14:904-912(2000).
Di Padova M., J. Biol. Chem. 278:36496-36504(2003).
Aliases: AATF antibody, AATF_HUMAN antibody, Apoptosis antagonizing transcription factor antibody, Apoptosis-antagonizing transcription factor antibody, BFR2 antibody, CHE 1 antibody, CHE1 antibody, DED antibody, Protein AATF antibody, Rb binding protein Che 1 antibody, Rb-binding protein Che-1 antibody

UniProt

Q9NY61

途径

Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome