AATF 抗体 (AA 451-560)
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- 抗原 See all AATF 抗体
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
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抗原表位
- AA 451-560
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AATF antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Pig,Horse,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AATF
- 亚型
- IgG
- Top Product
- Discover our top product AATF Primary Antibody
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anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 151-250) antibody
AATF 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibodyAATF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 1-39) antibodyAATF 适用: 人, 小鼠 WB, IF 宿主: 大鼠 Monoclonal 1B2D8 unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 240-438) antibodyAATF 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 237-523) antibodyAATF 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibodyAATF 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibodyAATF 适用: 人, 猴 WB, IHC, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibodyAATF 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (N-Term) antibodyAATF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis Antagonizing Transcription Factor (AATF) (AA 6-294) antibodyAATF 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 别名
- AATF (AATF 产品)
- 别名
- AATF antibody, ded antibody, che1 antibody, che-1 antibody, cb109 antibody, sb:cb109 antibody, wu:fc13d05 antibody, zgc:162071 antibody, CHE-1 antibody, CHE1 antibody, DED antibody, 4933415H02Rik antibody, 5830465M17Rik antibody, Che-1 antibody, Trb antibody, Ded antibody, apoptosis antagonizing transcription factor antibody, Apoptosis antagonizing transcription factor antibody, apoptosis antagonizing transcription factor S homeolog antibody, AATF antibody, aatf antibody, BFR2 antibody, NAEGRDRAFT_56916 antibody, Aatf antibody, aatf.S antibody
- 背景
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Synonyms: DED, BFR2, CHE1, CHE-1, Protein AATF, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1, AATF, HSPC277
Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
- 基因ID
- 26574
- UniProt
- Q9NY61
- 途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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