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VEGF 抗体

VEGF 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7009727
发货至: 中国
  • 抗原 See all VEGF 抗体
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    适用
    • 76
    • 46
    • 34
    • 18
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 23
    • 12
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 58
    • 31
    • 1
    单克隆
    标记
    • 39
    • 13
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    • 5
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    This VEGF antibody is un-conjugated
    应用范围
    • 77
    • 55
    • 23
    • 19
    • 15
    • 14
    • 12
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Monoclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human VEGFA
    亚型
    IgG
    Top Product
    Discover our top product VEGF Primary Antibody
  • 应用备注
    WB 1:500-1:1000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    别名
    VEGF (VEGF 产品)
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vegf antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor antibody, vascular endothelial growth factor precursor antibody, VEGFA antibody, Vegfa antibody, vegfa.L antibody, VEGF antibody, vegf antibody
    背景
    This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
    分子量

    Observed_MW: 20 kDa

    Calculated_MW: 15-27 kDa/34-45 kDa

    基因ID
    7422
    UniProt
    P15692
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