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VEGF 抗体

VEGF 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 小鸡 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN674829
发货至: 中国
  • 抗原 See all VEGF 抗体
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    适用
    • 76
    • 46
    • 34
    • 17
    • 16
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, 犬, Cow, 小鸡
    宿主
    • 51
    • 24
    • 12
    • 2
    • 2
    • 1
    克隆类型
    • 57
    • 32
    • 1
    多克隆
    标记
    • 39
    • 13
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGF antibody is un-conjugated
    应用范围
    • 77
    • 55
    • 23
    • 20
    • 15
    • 13
    • 11
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 兔, 大鼠
    预测反应
    Dog,Cow,Chicken,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human VEGF
    亚型
    IgG
    Top Product
    Discover our top product VEGF Primary Antibody
  • 应用备注
    WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • Gao, Wen, Yang, Lu, Tong, Huang, Liu, Tang: "Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis." in: PLoS ONE, Vol. 8, Issue 7, pp. e69309, (2013) (PubMed).

    Lv, Xu, Zhang, Wang, Wang, He, Wang: "Repeated abortion affects subsequent pregnancy outcomes in BALB/c mice." in: PLoS ONE, Vol. 7, Issue 10, pp. e48384, (2012) (PubMed).

  • 抗原
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    别名
    VEGF (VEGF 产品)
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vegf antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor antibody, vascular endothelial growth factor precursor antibody, VEGFA antibody, Vegfa antibody, vegfa.L antibody, VEGF antibody, vegf antibody
    背景

    Synonyms: Vascuoar endothelial growth factor A, VEGF A, vascular endothelial growth factor A isoform 2 precursor, MGC70609, MVCD1, VEGF, VPF, VEGFA_HUMAN, VEGF-A, Vascular permeability factor (VPF),

    Background: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.Function : Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

    分子量
    23kDa
    基因ID
    7422
    UniProt
    P15692
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