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ROCK1 抗体

KO Validated ROCK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255137
发货至: 中国
  • 抗原 See all ROCK1 抗体
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    适用
    • 78
    • 57
    • 55
    • 5
    • 3
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    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 71
    • 8
    克隆类型
    • 58
    • 21
    多克隆
    标记
    • 38
    • 5
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    • 3
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    • 3
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    • 1
    This ROCK1 antibody is un-conjugated
    应用范围
    • 68
    • 27
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    • 20
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    • 14
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    • 11
    • 11
    • 8
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    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    This antibody ist KO validated.
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    Recombinant fusion protein of human ROCK1 (NP_005397.1).
    亚型
    IgG
    Top Product
    Discover our top product ROCK1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    别名
    ROCK1 (ROCK1 产品)
    别名
    LOC100229794 antibody, CG9774 antibody, DROK antibody, DRhk antibody, DRok antibody, Dmel\\CG9774 antibody, Drok antibody, ROCK antibody, ROCK-1 antibody, ROCK1 antibody, ROK antibody, ROKalpha/beta antibody, Rhk antibody, RhoK antibody, Rock antibody, Rok antibody, dROK antibody, dRok antibody, drok antibody, 1110055K06Rik antibody, Rock-I antibody, P160Rock antibody, ROCK-I antibody, P160ROCK antibody, p160ROCK antibody, Rho associated coiled-coil containing protein kinase 1 antibody, Rho kinase antibody, Rho-associated coiled-coil containing protein kinase 1 antibody, Rho-associated, coiled-coil containing protein kinase 1 antibody, ROCK1 antibody, Rok antibody, Rock1 antibody, rock1 antibody
    背景
    This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
    分子量

    Observed_MW: 158 kDa

    Calculated_MW: 158 kDa

    基因ID
    6093
    UniProt
    Q13464
    途径
    Microtubule Dynamics, WNT signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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