ROCK1 抗体 (AA 400-660)
Our Local Distributor
北京 101111
Quick Overview for ROCK1 抗体 (AA 400-660) (ABIN6147066)
抗原
See all ROCK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 400-660
-
序列
- YSNRRYLSSA NPNDNRTSSN ADKSLQESLQ KTIYKLEEQL HNEMQLKDEM EQKCRTSNIK LDKIMKELDE EGNQRRNLES TVSQIEKEKM LLQHRINEYQ RKAEQENEKR RNVENEVSTL KDQLEDLKKV SQNSQLANEK LSQLQKQLEE ANDLLRTESD TAVRLRKSHT EMSKSISQLE SLNRELQERN RILENSKSQT DKDYYQLQAI LEAERRDRGH DSEMIGDLQA RITSLQEEVK HLKHNLEKVE GERKEAQDML N
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human ROCK1 (NP_005397.1).
-
亚型
- IgG
-
-
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (N-Term) antibody
KO Validated ROCK1 适用: 人 WB, IP, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1001-1200) antibodyROCK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 401-510) antibodyROCK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibodyROCK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 405-668) antibodyROCK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyKD Validated ROCK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3460 unconjugated Recombinant Antibody
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyKO Validated ROCK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3465 unconjugated Recombinant Antibody
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyKD Validated ROCK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3600 unconjugated Recombinant Antibody
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyKD Validated ROCK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2065 unconjugated Recombinant Antibody
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
-
别名
- ROCK1
-
背景
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.,ROCK1,P160ROCK,ROCK-I,Cancer,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,ROCK1
-
分子量
- 158 kDa
-
基因ID
- 6093
-
UniProt
- Q13464
-
途径
- Microtubule Dynamics, WNT signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
抗原
-
