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ROCK1 抗体 (AA 405-668)

ROCK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167999
发货至: 中国
  • 抗原 See all ROCK1 抗体
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    抗原表位
    • 16
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    • 3
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    • 1
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    • 1
    • 1
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    AA 405-668
    适用
    • 78
    • 58
    • 56
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 71
    • 8
    克隆类型
    • 58
    • 21
    多克隆
    标记
    • 38
    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
    This ROCK1 antibody is un-conjugated
    应用范围
    • 68
    • 27
    • 26
    • 19
    • 17
    • 14
    • 13
    • 11
    • 10
    • 8
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Rho-associated protein kinase 1 protein (405-668AA)
    亚型
    IgG
    Top Product
    Discover our top product ROCK1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
    别名
    ROCK1 (ROCK1 产品)
    别名
    LOC100229794 antibody, CG9774 antibody, DROK antibody, DRhk antibody, DRok antibody, Dmel\\CG9774 antibody, Drok antibody, ROCK antibody, ROCK-1 antibody, ROCK1 antibody, ROK antibody, ROKalpha/beta antibody, Rhk antibody, RhoK antibody, Rock antibody, Rok antibody, dROK antibody, dRok antibody, drok antibody, 1110055K06Rik antibody, Rock-I antibody, P160Rock antibody, ROCK-I antibody, P160ROCK antibody, p160ROCK antibody, Rho associated coiled-coil containing protein kinase 1 antibody, Rho kinase antibody, Rho-associated coiled-coil containing protein kinase 1 antibody, Rho-associated, coiled-coil containing protein kinase 1 antibody, ROCK1 antibody, Rok antibody, Rock1 antibody, rock1 antibody
    背景

    Background: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.

    Aliases: coiled-coil-containing protein kinase 1 antibody, coiled-coil-containing protein kinase I antibody, MGC131603 antibody, MGC43611 antibody, p160 Rhoassociated coiled coil-forming protein kinase antibody, p160 ROCK-1 antibody, p160 ROCK1 antibody, p160ROCK antibody, PRO0435 antibody, Renal carcinoma antigen NY REN 35 antibody, Renal carcinoma antigen NY-REN-35 antibody, Rho associated coiled coil containing protein kinase 1 antibody, Rho associated protein kinase 1 antibody, Rho kinase antibody, Rho-alpha kinase antibody, Rho-associated antibody, Rho-associated protein kinase 1 antibody, ROCK I antibody, ROCK-I antibody, ROCK1 antibody, ROCK1_HUMAN antibody, Rok antibody, rokalpha antibody

    UniProt
    Q13464
    途径
    Microtubule Dynamics, WNT signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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