SARM1 抗体 (N-Term)
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- 抗原 See all SARM1 抗体
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
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抗原表位
- AA 30-80, N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), ELISA
- 特异性
- At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.
- 纯化方法
- SARM Antibody is affinity chromatography purified via peptide column.
- 免疫原
- SARM antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SARM. The immunogen is located within amino acids 30 - 80 of SARM.
- 亚型
- IgG
- Top Product
- Discover our top product SARM1 Primary Antibody
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anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (AA 340-380) antibody
SARM1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 适用: 人, 小鼠 WB, IHC (p), IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) antibodySARM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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SARM antibody can be used for detection of SARM by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SARM Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SARM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
- 别名
- SARM (SARM1 产品)
- 别名
- A830091I15Rik antibody, C78606 antibody, MyD885 antibody, Sarm antibody, MyD88-5 antibody, SAMD2 antibody, SARM antibody, sterile alpha and TIR motif containing 1 antibody, sterile alpha and HEAT/Armadillo motif containing 1 antibody, SARM1 antibody, Sarm1 antibody, sarm1 antibody
- 背景
- SARM Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-κ,B, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
- 基因ID
- 23098
- NCBI登录号
- NP_055892
- UniProt
- Q6SZW1
- 途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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