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DPF3 抗体 (AA 1-100) (Alexa Fluor 350)

DPF3 适用: 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN6976496
发货至: 中国
  • 抗原 See all DPF3 抗体
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 32
    • 23
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 46
    克隆类型
    • 46
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DPF3 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 39
    • 18
    • 12
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CERD4
    亚型
    IgG
    Top Product
    Discover our top product DPF3 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
    别名
    CERD4 (DPF3 产品)
    别名
    BAF45C antibody, CERD4 antibody, 2810403B03Rik antibody, 6530402L11Rik antibody, C78788 antibody, cer-d4 antibody, si:ch211-268e23.1 antibody, wu:fj43h12 antibody, double PHD fingers 3 antibody, D4, zinc and double PHD fingers, family 3 antibody, DPF3 antibody, Dpf3 antibody, dpf3 antibody
    背景

    Synonyms: Zinc finger protein DPF3, DPF3, BRG1-associated factor 45C, BAF45C, Zinc finger protein cer-d4, BAF45C, CERD4

    Background: Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.

    基因ID
    8110
    UniProt
    Q92784
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