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DPF3 产品

(D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Categories

Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development (By similarity). Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Featured DPF3 Categories

DPF3 抗体

High quality antibodies with extensive validation data.

DPF3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DPF3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
  • (4)
Cat. No. ABIN2775708
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN2775709
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN5675567
Quantity 100 μL
Datasheet Datasheet

Recommended DPF3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092223
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134531
Quantity 1 mg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1655185
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DPF3 Products

Theodorou, Speletas, Mamara, Papachristopoulou, Lazou, Scorilas, Katsantoni: "Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia." in: PLoS ONE, Vol. 8, Issue 10, pp. e76155, (2013) (PubMed).

Hoyal, Kammerer, Roth, Reneland, Marnellos, Kiechle, Schwarz-Boeger, Griffiths, Ebner, Rehbock, Nelson, Braun: "Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases." in: Journal of carcinogenesis, Vol. 4, pp. 13, (2005) (PubMed).

Synonyms and alternative names related to DPF3

double PHD fingers 3 (DPF3), D4, zinc and double PHD fingers, family 3 (Dpf3), double PHD fingers 3 (Dpf3), D4, zinc and double PHD fingers, family 3 (dpf3), 2810403B03Rik, 6530402L11Rik, BAF45C, C78788, cer-d4, CERD4, si:ch211-268e23.1, wu:fj43h12

Protein level used designations for DPF3

  • cer-d4
  • zinc finger protein DPF3
  • zinc finger protein cer-d4
  • BRG1-associated factor 45C
  • D4 zinc and double PHD finger family 3
  • cerebellum D4
  • D4 zinc and double PHD fingers family 3 protein
  • fj43h12
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