DPF3 抗体 (N-Term)
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- 抗原 See all DPF3 抗体
- DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- IHNPLKALGD QFYKEAIEHC RSYNSRLCAE RSVRLPFLDS QTGVAQNNCY
- 预测反应
- Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against Dpf3. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product DPF3 Primary Antibody
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anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (Middle Region) antibody
DPF3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (N-Term) antibodyDPF3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 1-100) antibodyDPF3 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 108-157) antibodyDPF3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (N-Term) antibodyDPF3 适用: 人, 小鼠, 兔, 豚鼠, 马, 猴, Pig, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 71-120) antibodyDPF3 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马, Cow, 犬, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 1-196) antibodyDPF3 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 90-200) antibodyDPF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 356 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
- 别名
- Dpf3 (DPF3 产品)
- 别名
- BAF45C antibody, CERD4 antibody, 2810403B03Rik antibody, 6530402L11Rik antibody, C78788 antibody, cer-d4 antibody, si:ch211-268e23.1 antibody, wu:fj43h12 antibody, double PHD fingers 3 antibody, D4, zinc and double PHD fingers, family 3 antibody, DPF3 antibody, Dpf3 antibody, dpf3 antibody
- 背景
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Dpf3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Dpf3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
Alias Symbols: 2810403B03Rik, C78788, CERD4, cer-d4, BAF45C, 6530402L11Rik
Protein Size: 356 - 分子量
- 40 kDa
- 基因ID
- 70127
- NCBI登录号
- NM_058212, NP_478119
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